SCHEMBL8835013

SCHEMBL8835013

CCCC1CCC(CCC2CCC(c3ccc(Cl)c(OC(F)(F)C(F)C(F)(F)F)c3F)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 19/20 0.33
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8834504 0.77 CYP2C9 (0.35) CYP2C9
SCHEMBL7913546 0.77 DRD2 (0.37) OPRL1CYP2C9
SCHEMBL7913730 0.75 CYP2C9 (0.36) CYP2C9
SCHEMBL8834541 0.74 CYP2C9 (0.37) CYP2C9
SCHEMBL9247695 0.73 OPRL1 (0.40) OPRL1CYP2C9
SCHEMBL9239246 0.73 DRD2 (0.36) OPRL1CYP2C9
SCHEMBL8834657 0.73 CYP2C9 (0.34) CYP2C9
SCHEMBL7917364 0.72 CYP2C9 (0.46) CYP2C9
SCHEMBL7913636 0.72 CYP2C9 (0.39) CYP2C9
SCHEMBL8833908 0.71 CYP2C9 (0.38) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed