Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 6/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096511 | 0.93 | EED (0.40) | EEDKCNA3MTNR1AMTNR1BMAOA | |
| SCHEMBL2094789 | 0.89 | EED (0.44) | EEDKCNA3MTNR1AMTNR1BMAOA | |
| SCHEMBL2091923 | 0.84 | KCNA3 (0.40) | EEDKCNA3MTNR1AMTNR1BMAOA | |
| SCHEMBL6952349 | 0.82 | EED (0.42) | EEDKCNA3MTNR1AMTNR1BMAOA | |
| SCHEMBL2096585 | 0.82 | EED (0.42) | EEDKCNA3MTNR1AMTNR1BMAOA | |
| SCHEMBL347860 | 0.82 | MTNR1A (0.47) | EEDKCNA3MTNR1AMTNR1BMAOA | |
| SCHEMBL2095886 | 0.81 | KCNA3 (0.43) | EEDKCNA3MTNR1AMTNR1BMAOA | |
| SCHEMBL2095736 | 0.81 | EED (0.46) | EEDKCNA3MTNR1AMTNR1BMAOA | |
| SCHEMBL452968 | 0.78 | EED (0.40) | EEDKCNA3MTNR1AMTNR1BMAOA | |
| SCHEMBL3793134 | 0.78 | MTNR1A (0.49) | EEDKCNA3MTNR1AMTNR1BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606078-A | ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0678514-A1 | 3,5-Disubstituted tetrahydrofuran-2-ones | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |