Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.71 |
| ▸ | GAA | P10253 | 8/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | HPGD | P15428 | 5/20 | 0.71 |
| ▸ | GLA | P06280 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | FHIT | P49789 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993105 | 0.87 | KDM4E (0.73) | KDM4EGAAHSD17B10KMT2AHPGD | |
| SCHEMBL7917900 | 0.86 | KDM4E (0.68) | KDM4EGAAHSD17B10KMT2AHPGD | |
| SCHEMBL15984892 | 0.84 | KDM4E (0.74) | KDM4EGAAHSD17B10KMT2AHPGD | |
| SCHEMBL14326166 | 0.83 | KDM4E (0.64) | KDM4EGAAHSD17B10KMT2AHPGD | |
| SCHEMBL9463878 | 0.80 | ALDH1A1 (1.00) | KDM4EGAAHSD17B10KMT2AHPGD | |
| SCHEMBL11195848 | 0.79 | KDM4E (0.74) | KDM4EGAAHSD17B10KMT2AHPGD | |
| SCHEMBL6109279 | 0.78 | KDM4E (0.77) | KDM4EGAAHSD17B10KMT2AHPGD | |
| SCHEMBL9464109 | 0.77 | KDM4E (0.76) | KDM4EGAAHSD17B10KMT2AHPGD | |
| SCHEMBL11193363 | 0.76 | KDM4E (0.68) | KDM4EGAAHSD17B10KMT2AHPGD | |
| SCHEMBL11435073 | 0.76 | KDM4E (0.68) | KDM4EGAAHSD17B10KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |