Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.34 |
| ▸ | PDE2A | O00408 | 6/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835457 | 1.00 | EPHX2 (0.34) | EPHX2PDE2AKDM1ACTSKNAAA | |
| SCHEMBL8835324 | 0.87 | PDE2A (0.34) | EPHX2PDE2AKDM1AP2RX7HCRTR1 | |
| SCHEMBL8835318 | 0.87 | PDE2A (0.34) | EPHX2PDE2AKDM1AP2RX7HCRTR1 | |
| SCHEMBL8835502 | 0.85 | PDE2A (0.33) | EPHX2PDE2AKDM1AP2RX7 | |
| SCHEMBL8835498 | 0.85 | PDE2A (0.33) | EPHX2PDE2AKDM1AP2RX7 | |
| SCHEMBL8835568 | 0.85 | — | — | |
| SCHEMBL8835565 | 0.85 | — | — | |
| SCHEMBL8835054 | 0.83 | EPHX2 (0.37) | EPHX2PDE2A | |
| SCHEMBL8835064 | 0.83 | EPHX2 (0.37) | EPHX2PDE2A | |
| SCHEMBL8835703 | 0.83 | HCRTR2 (0.34) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |