Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835711 | 1.00 | HCRTR2 (0.34) | HCRTR2HTR2AHTR2CHTR2BUSP5 | |
| SCHEMBL4921898 | 0.90 | HTR2A (0.36) | HCRTR2HTR2AHTR2CHTR2BUSP5 | |
| SCHEMBL9480887 | 0.86 | USP5 (0.34) | HCRTR2HTR2AHTR2CHTR2BUSP5 | |
| SCHEMBL9480907 | 0.86 | USP5 (0.34) | HCRTR2HTR2AHTR2CHTR2BUSP5 | |
| SCHEMBL14316105 | 0.86 | USP5 (0.34) | HCRTR2HTR2AHTR2CHTR2BUSP5 | |
| SCHEMBL8771249 | 0.86 | USP5 (0.34) | HCRTR2HTR2AHTR2CHTR2BUSP5 | |
| SCHEMBL8835137 | 0.86 | KDM1A (0.41) | HTR2A | |
| SCHEMBL8835140 | 0.86 | KDM1A (0.41) | HTR2A | |
| SCHEMBL8836077 | 0.86 | — | — | |
| SCHEMBL8836069 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |