Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 6/20 | 0.33 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623347 | 0.89 | MAPT (0.40) | PGRADORA3ADRA2CSLC6A2HTR2B | |
| SCHEMBL11621723 | 0.88 | PGR (0.36) | PGRADORA3ADRA2CSLC6A2HTR2B | |
| SCHEMBL11620422 | 0.81 | KDM4E (0.31) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11617785 | 0.81 | PGR (0.36) | PGRADORA3ADRA2CSLC6A2HTR2B | |
| SCHEMBL11618020 | 0.80 | PGR (0.31) | PGRADORA3ADRA2CSLC6A2HTR2B | |
| SCHEMBL11515071 | 0.79 | — | — | |
| SCHEMBL10790152 | 0.78 | HCAR2 (0.34) | ALDH1A1KEAP1NFE2L2HCAR2TBXA2R | |
| SCHEMBL10891016 | 0.78 | HCAR2 (0.34) | ALDH1A1KEAP1NFE2L2HCAR2TBXA2R | |
| SCHEMBL11659917 | 0.77 | CNR1 (0.37) | PGRADORA3ADRA2CSLC6A2HTR2B | |
| SCHEMBL8432838 | 0.77 | PDE4D (0.33) | PDE4DKDM4EALDH1A1HKDC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658897-A | MUSCLE RELAXANTS AND OCULAR HYPOTENSIVE AGENTS | ALLERGAN (US) | 1997-08-19 | — | — | US | disclosed |