Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835582 | 0.91 | SPHK1 (0.52) | SPHK1SPHK2 | |
| SCHEMBL8835569 | 0.90 | CYP2C9 (0.35) | SPHK1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8835370 | 0.88 | CYP2C9 (0.40) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL8835097 | 0.87 | SPHK1 (0.56) | SPHK1SPHK2MEN1KMT2A | |
| SCHEMBL8834906 | 0.85 | CYP2C9 (0.38) | SPHK1CYP2C9SPHK2ALDH1A1LMNA | |
| SCHEMBL9477417 | 0.84 | SPHK1 (0.42) | SPHK1CYP2C9SPHK2P2RY14ALDH1A1 | |
| SCHEMBL9477410 | 0.84 | SPHK1 (0.42) | SPHK1CYP2C9SPHK2P2RY14ALDH1A1 | |
| SCHEMBL9477428 | 0.84 | SPHK1 (0.42) | SPHK1CYP2C9SPHK2P2RY14ALDH1A1 | |
| SCHEMBL9477393 | 0.84 | SPHK1 (0.42) | SPHK1CYP2C9SPHK2P2RY14ALDH1A1 | |
| SCHEMBL8454721 | 0.83 | SPHK1 (0.41) | SPHK1CYP2C9SPHK2P2RY14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |