Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835097 | 0.96 | SPHK1 (0.56) | SPHK1SPHK2 | |
| SCHEMBL8835504 | 0.91 | SPHK1 (0.40) | SPHK1SPHK2 | |
| SCHEMBL8835561 | 0.88 | SPHK1 (0.50) | SPHK1SPHK2HRH3NPC1RAB9A | |
| SCHEMBL8835569 | 0.86 | CYP2C9 (0.35) | SPHK1NPC1RAB9A | |
| SCHEMBL9509123 | 0.85 | SPHK1 (0.54) | SPHK1SPHK2HRH3RARBTSHR | |
| SCHEMBL9509118 | 0.85 | SPHK1 (0.54) | SPHK1SPHK2HRH3RARBTSHR | |
| SCHEMBL9509132 | 0.85 | SPHK1 (0.54) | SPHK1SPHK2HRH3RARBTSHR | |
| SCHEMBL9509128 | 0.85 | SPHK1 (0.54) | SPHK1SPHK2HRH3RARBTSHR | |
| SCHEMBL8835448 | 0.84 | SPHK1 (0.53) | SPHK1SPHK2 | |
| SCHEMBL9476821 | 0.84 | SPHK1 (0.56) | SPHK1SPHK2RARBTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |