Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | USP5 | P45974 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835549 | 1.00 | HTR2A (0.33) | HTR2AHTR2CHTR2BHDAC2GRIA4 | |
| SCHEMBL8835089 | 0.97 | USP5 (0.32) | HTR2AHTR2CHTR2BHDAC2GRIA4 | |
| SCHEMBL8835085 | 0.97 | USP5 (0.32) | HTR2AHTR2CHTR2BHDAC2GRIA4 | |
| SCHEMBL17070830 | 0.89 | HTR2A (0.35) | HTR2AHTR2CHTR2BHDAC2GRIA4 | |
| SCHEMBL9166201 | 0.88 | USP5 (0.33) | HTR2AHTR2CHTR2BHDAC2GRIA4 | |
| SCHEMBL8633516 | 0.88 | USP5 (0.33) | HTR2AHTR2CHTR2BHDAC2GRIA4 | |
| SCHEMBL8633522 | 0.88 | USP5 (0.33) | HTR2AHTR2CHTR2BHDAC2GRIA4 | |
| SCHEMBL8633520 | 0.88 | USP5 (0.33) | HTR2AHTR2CHTR2BHDAC2GRIA4 | |
| SCHEMBL8633514 | 0.88 | USP5 (0.33) | HTR2AHTR2CHTR2BHDAC2GRIA4 | |
| SCHEMBL10027426 | 0.88 | USP5 (0.33) | HTR2AHTR2CHTR2BHDAC2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |