Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835578 | 1.00 | HDAC2 (0.38) | HDAC2MAP1LC3BMAOAMAOBPTGS1 | |
| SCHEMBL8835205 | 0.95 | HDAC2 (0.35) | HDAC2MAP1LC3BMAOAMAOBPTGS1 | |
| SCHEMBL8835208 | 0.95 | HDAC2 (0.35) | HDAC2MAP1LC3BMAOAMAOBPTGS1 | |
| SCHEMBL8835537 | 0.82 | HTR2C (0.50) | HDAC2MAOB | |
| SCHEMBL8836056 | 0.82 | HTR2A (0.33) | HDAC2MAOBKDM1A | |
| SCHEMBL8836053 | 0.82 | HTR2A (0.33) | HDAC2MAOBKDM1A | |
| SCHEMBL8835534 | 0.82 | HTR2C (0.50) | HDAC2MAOB | |
| SCHEMBL8836059 | 0.82 | HTR2A (0.33) | HDAC2MAOBKDM1A | |
| SCHEMBL21338789 | 0.82 | MAP1LC3B (0.37) | HDAC2MAP1LC3BPTGS1PTGS2KDM1A | |
| SCHEMBL8835086 | 0.81 | HDAC2 (0.37) | HDAC2MAP1LC3BMAOAMAOBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |