Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835606 | 1.00 | MME (0.58) | MMENPSR1ACEFPR2CYP1A2 | |
| SCHEMBL608817 | 0.86 | FOLH1 (0.54) | MMEACENAALAD2L3MBTL1FOLH1 | |
| SCHEMBL608818 | 0.86 | FOLH1 (0.54) | MMEACENAALAD2L3MBTL1FOLH1 | |
| SCHEMBL9068541 | 0.84 | MME (0.70) | MMENPSR1ACECYP1A2NAALAD2 | |
| SCHEMBL7379335 | 0.84 | MME (0.70) | MMENPSR1ACECYP1A2NAALAD2 | |
| SCHEMBL6079626 | 0.84 | MME (0.65) | MMEACECPA1ACE2 | |
| SCHEMBL6079620 | 0.84 | MME (0.65) | MMEACECPA1ACE2 | |
| SCHEMBL8422124 | 0.81 | MME (0.50) | MMENPSR1ACECYP1A2NAALAD2 | |
| SCHEMBL27925841 | 0.81 | MME (0.50) | MMENPSR1FPR2CYP1A2NAALAD2 | |
| SCHEMBL157547 | 0.80 | MME (0.61) | MMENPSR1ACECYP1A2NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016086015-A1 | MYOGLOBIN-BASED CATALYSTS FOR CARBENE TRANSFER REACTIONS | UNIVERSITY OF ROCHESTER (US) | 2016-06-02 | — | — | WO | claimed |
| WO-2016086015-A1 | MYOGLOBIN-BASED CATALYSTS FOR CARBENE TRANSFER REACTIONS | UNIVERSITY OF ROCHESTER (US) | 2016-06-02 | — | — | WO | disclosed |
| US-5686310-A | Method for determination of the amount of either phosphotyrosine or phosphoserine in a protein | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 1997-11-11 | — | — | US | disclosed |