Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771249 | 1.00 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9480887 | 1.00 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL14316105 | 1.00 | USP5 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL4921898 | 0.96 | HTR2A (0.36) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9480546 | 0.89 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8517973 | 0.89 | CYP2C9 (0.35) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9250475 | 0.89 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9250486 | 0.89 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9312466 | 0.89 | CYP2C9 (0.35) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9250481 | 0.89 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185098-A | Liquid crystalline mixtures containing 3,4-difluorophenyl-substituted bicyclohexyls | HOFFMANN-LA ROCHE INC. (US) | 1993-02-09 | — | — | US | disclosed |