Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 7/20 | 0.58 |
| ▸ | THRA | P10827 | 5/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8836103 | 0.95 | THRB (0.59) | AKT1THRBTHRAPTGS2MEN1 | |
| SCHEMBL8836177 | 0.94 | THRB (0.60) | AKT1THRBTHRAPTGS2MEN1 | |
| SCHEMBL8836289 | 0.94 | THRB (0.65) | AKT1THRBTHRAPTGS2MEN1 | |
| SCHEMBL8836309 | 0.90 | AKT1 (0.63) | AKT1THRBTHRAPTGS2MEN1 | |
| SCHEMBL8836284 | 0.89 | THRB (0.66) | AKT1THRBTHRAPTGS2MEN1 | |
| SCHEMBL8835828 | 0.87 | THRB (0.67) | THRBTHRAPTGS2MEN1KMT2A | |
| Hexane SCHEMBL27513037 | 0.87 | AKT1 (0.73) | AKT1THRBTHRAMEN1KMT2A | |
| SCHEMBL8835694 | 0.83 | AKT1 (0.68) | AKT1THRBTHRAPTGS2MEN1 | |
| SCHEMBL8836141 | 0.83 | THRB (0.63) | AKT1THRBTHRAMEN1KMT2A | |
| SCHEMBL8836152 | 0.82 | THRB (0.56) | THRBTHRAPTGS2KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674576-A | A LIGHT MODULATING LAYER COMPOSED OF LIQUID CRYSTAL AND HIGH POLYMER RESIN IS SANDWHICHED BETWEEN TWO SUBSTRATES HAVING ELECTRODE LAYERS, MONOMERS ARE OF(METH)ACRYLOYL COMPOUNDS WITH STIBENE OR (METH)ACRYLOYL WITH DIOXANE OR DIOXOLANES | NEC CORPORATION (JP) | 1997-10-07 | — | — | US | disclosed |