Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 12/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737983 | 0.80 | TSHR (0.60) | ALDH1A1TP53TSHRHIF1AHSD17B10 | |
| SCHEMBL15129943 | 0.80 | HCAR2 (0.53) | HCAR2ATMALDH1A1TP53TSHR | |
| SCHEMBL15129940 | 0.80 | HCAR2 (0.53) | HCAR2ATMALDH1A1TP53TSHR | |
| SCHEMBL4140289 | 0.79 | TDP1 (0.41) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL24040550 | 0.78 | HCAR2 (0.65) | HCAR2ATMALDH1A1TP53TSHR | |
| SCHEMBL19029663 | 0.78 | HCAR2 (0.65) | HCAR2ATMALDH1A1TP53TSHR | |
| SCHEMBL19029632 | 0.78 | HCAR2 (0.65) | HCAR2ATMALDH1A1TP53TSHR | |
| SCHEMBL27407116 | 0.78 | HCAR2 (0.65) | HCAR2ATMALDH1A1TP53TSHR | |
| SCHEMBL1246093 | 0.78 | HCAR2 (0.65) | HCAR2ATMALDH1A1TP53TSHR | |
| SCHEMBL637852 | 0.78 | HCAR2 (0.65) | HCAR2ATMALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604573-A | Developing unit with a smoothing plate | KONICA CORPORATION (JP) | 1997-02-18 | — | — | US | disclosed |