SCHEMBL8836738

SCHEMBL8836738

CCCC/C=C/C(CCC)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 2/20 0.44
F3 P13726 2/20 0.44
PPARG P37231 4/20 0.40
TERT O14746 3/20 0.40
PTPN1 P18031 3/20 0.40
PPARD Q03181 3/20 0.40
PPARA Q07869 3/20 0.40
CYP1A2 P05177 2/20 0.40
MAPT P10636 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
BLM P54132 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CHRM1 P11229 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
FABP4 P15090 2/20 0.40
GMNN O75496 1/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1771112 1.00 F7 (0.44) F7F3PPARGTERTPTPN1
SCHEMBL3273780 0.92 F7 (0.44) F7F3PPARGTERTPTPN1
SCHEMBL2710298 0.92 F7 (0.44) F7F3PPARGTERTPTPN1
SCHEMBL16927607 0.89 GPR84 (0.48) PPARGTERTPPARDCYP1A2MAPT
SCHEMBL14039917 0.89 GPR84 (0.48) PPARGTERTPPARDCYP1A2MAPT
SCHEMBL29155796 0.89 GPR84 (0.48) PPARGTERTPPARDCYP1A2MAPT
SCHEMBL28238172 0.89 GPR84 (0.48) PPARGTERTPPARDCYP1A2MAPT
SCHEMBL16927610 0.89 GPR84 (0.48) PPARGTERTPPARDCYP1A2MAPT
SCHEMBL1771141 0.86 F7 (0.46) F7F3PPARGTERTPTPN1
SCHEMBL1771144 0.86 F7 (0.46) F7F3PPARGTERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
US-5639900-A MOLYBDENUM OR TUGSTEN COMPLEXES METTON AMERICA, INC. (US) 1997-06-17 US disclosed
US-5606085-A PHYSICAL ACTIVATION OF TRANSITIONAL BASED COMPLEX METTON AMERICA, INC. (US) 1997-02-25 US disclosed