SCHEMBL8836865

SCHEMBL8836865

O=C(O)C(=CCCO)CCCO

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 1/20 0.44
GPR84 Q9NQS5 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
GRIK1 P39086 2/20 0.34
SQLE Q14534 2/20 0.32
GRIK2 Q13002 1/20 0.32
CPB1 P15086 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
ABAT P80404 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28502381 0.86 GRIK1 (0.34) CAMK2AGRIK1GRIK2CPB1FNTA
SCHEMBL11034343 0.85 GRIK1 (0.46) GRIK1GRIK2
SCHEMBL11050685 0.82 EP300 (0.48) GPR84FFAR1FFAR4
SCHEMBL465438 0.82 EP300 (0.48) GPR84FFAR1FFAR4
Acrylic Acid SCHEMBL1273801 0.82 LMNA (0.37) CAMK2AGPR84FFAR1FFAR4GRIK1
SCHEMBL1897827 0.82 EGLN1 (0.41) CAMK2AGPR84FFAR1FFAR4GRIK1
SCHEMBL3669205 0.80 GRIK1 (0.32) GRIK1GRIK2CPB1ABAT
SCHEMBL11480862 0.80 GRIK1 (0.46) CAMK2AGPR84FFAR1FFAR4GRIK1
SCHEMBL9651125 0.80 GRIK1 (0.43) GRIK1GRIK2CPB1
SCHEMBL7150124 0.79 GRIK1 (0.49) GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0771912-A1 Antifragmentation plates of polymethylmethacrylate ATOHAAS HOLDING C.V. (NL) 1997-05-07 EP disclosed