Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.58 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | ACACA | Q13085 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20827825 | 1.00 | THRB (0.58) | THRBACACBACACAELANEKMT2A | |
| SCHEMBL1516212 | 0.95 | THRB (0.63) | THRBACACBACACAELANEKMT2A | |
| SCHEMBL22148970 | 0.93 | THRB (0.51) | THRBACACBACACAELANEKMT2A | |
| SCHEMBL26362231 | 0.92 | ELANE (0.53) | THRBACACBACACAELANEKMT2A | |
| SCHEMBL26362357 | 0.92 | ELANE (0.53) | THRBACACBACACAELANEKMT2A | |
| SCHEMBL12073505 | 0.91 | THRB (0.55) | THRBELANEKMT2AALDH1A1ATM | |
| SCHEMBL14555152 | 0.91 | THRB (0.55) | THRBELANEKMT2AALDH1A1ATM | |
| SCHEMBL7219378 | 0.91 | THRB (0.58) | THRBACACBACACAELANEKMT2A | |
| SCHEMBL22258838 | 0.88 | THRB (0.59) | THRBKMT2AALDH1A1MAPTTHRA | |
| SCHEMBL7219385 | 0.88 | ELANE (0.66) | THRBELANEKMT2APLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3933009-B1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-08-16 | — | — | EP | disclosed |
| EP-3331965-B1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-05 | — | — | EP | disclosed |
| EP-3248060-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-09-02 | — | — | EP | disclosed |
| EP-3130650-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-07-04 | — | — | EP | disclosed |
| EP-2729550-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-02-21 | — | — | EP | disclosed |
| EP-2848676-B1 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2937401-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-04-05 | — | — | EP | disclosed |
| EP-3130650-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2017-02-15 | — | — | EP | disclosed |
| EP-3127989-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2017-02-08 | — | — | EP | disclosed |
| WO-2012038026-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |
| WO-2011160764-A1 | POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |
| WO-2010133278-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2010-11-25 | — | — | WO | disclosed |