Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306447 | 0.98 | SMN1; SMN2 (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL16544480 | 0.85 | DRD3 (0.33) | SMN1; SMN2 | |
| SCHEMBL28335459 | 0.84 | CA1 (0.34) | — | |
| SCHEMBL27975816 | 0.84 | MEN1 (0.37) | TSHRSLC6A4OPRM1SMN1; SMN2 | |
| SCHEMBL16544485 | 0.82 | CA1 (0.33) | — | |
| SCHEMBL16328038 | 0.81 | — | — | |
| SCHEMBL28203345 | 0.81 | MEN1 (0.36) | — | |
| SCHEMBL9575811 | 0.81 | MEN1 (0.36) | — | |
| SCHEMBL11198457 | 0.79 | — | — | |
| SCHEMBL7419427 | 0.78 | ATP1A1 (0.34) | SLC6A2SLC6A4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602136-A | Pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF-LILLY GMBH (DE) | 1997-02-11 | — | — | US | disclosed |