Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.68 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359445 | 0.93 | ITGB3 (0.58) | ITGB3ITGA2BF2FFAR1FFAR4 | |
| SCHEMBL7363456 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BF2KDM4EALOX15 | |
| SCHEMBL7421820 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BF2KDM4EKLKB1 | |
| SCHEMBL7354920 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BF2 | |
| SCHEMBL7363458 | 0.84 | ITGB3 (0.47) | ITGB3ITGA2BF2KDM4EALOX15 | |
| SCHEMBL8837116 | 0.84 | ITGB3 (0.72) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7325169 | 0.81 | ITGB3 (0.73) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| Trifluoroacetic Acid SCHEMBL7363241 | 0.81 | ITGB3 (0.66) | ITGB3ITGA2B | |
| SCHEMBL8837187 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2BKDM4EALOX15TSHR | |
| Trifluoroacetic Acid SCHEMBL7332946 | 0.79 | ITGB3 (0.70) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674863-A | BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR | GENENTECH, INC. (US) | 1997-10-07 | — | — | US | disclosed |
| US-5674865-A | BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR | GENENTECH, INC. (US) | 1997-10-07 | — | — | US | disclosed |