Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.61 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.61 |
| ▸ | CTSD | P07339 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | NPY4R | P50391 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837270 | 1.00 | BACE1 (0.61) | BACE1BACE2CTSDOPRD1NPY1R | |
| SCHEMBL30464728 | 0.95 | NPY1R (0.60) | BACE1BACE2CTSDOPRD1NPY1R | |
| SCHEMBL9848664 | 0.93 | OPRD1 (0.61) | BACE1BACE2CTSDOPRD1 | |
| SCHEMBL9848690 | 0.92 | OPRD1 (0.62) | BACE1BACE2CTSDOPRD1 | |
| SCHEMBL31062503 | 0.92 | OPRD1 (0.61) | BACE1BACE2CTSDOPRD1 | |
| SCHEMBL8332105 | 0.92 | FOLH1 (0.58) | BACE1BACE2OPRD1NPY1RNPY2R | |
| SCHEMBL8332107 | 0.92 | FOLH1 (0.58) | BACE1BACE2OPRD1NPY1RNPY2R | |
| SCHEMBL31062497 | 0.91 | OPRD1 (0.62) | BACE1BACE2CTSDOPRD1 | |
| SCHEMBL73897 | 0.91 | NPY4R (0.60) | BACE1BACE2CTSDOPRD1NPY1R | |
| SCHEMBL9848647 | 0.91 | OPRD1 (0.56) | BACE1BACE2CTSDOPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5628979-A | OLIGOPEPTIDES | ANTISOMA LIMITED (GB) | 1997-05-13 | — | — | US | claimed |
| EP-0527056-B1 | Novel reagent for tumour imaging and therapy | ANTISOMA LTD (GB) | 1996-10-09 | — | — | EP | claimed |
| WO-1993002708-A1 | NOVEL REAGENT FOR TUMOUR IMAGING AND THERAPY | ANTISOMA LIMITED (GB) | 1993-02-18 | — | — | WO | claimed |
| EP-0527056-A1 | Novel reagent for tumour imaging and therapy | ANTISOMA LIMITED (GB) | 1993-02-10 | — | — | EP | claimed |