Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26829548 | 0.87 | ATM (0.46) | RAB9ALMNAATMNPC1L3MBTL1 | |
| SCHEMBL1810919 | 0.84 | BAZ2B (0.43) | RAB9ALMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30514527 | 0.84 | KDM4E (0.38) | LMNAATML3MBTL1MAPTNFKB1 | |
| SCHEMBL24570280 | 0.84 | KDM4E (0.38) | LMNAATML3MBTL1MAPTNFKB1 | |
| SCHEMBL24362423 | 0.81 | BAZ2B (0.40) | RAB9ALMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29706757 | 0.81 | MAP3K5 (0.45) | LMNAMAPTTP53HTTALDH1A1 | |
| SCHEMBL23011990 | 0.81 | MAP3K5 (0.45) | LMNAMAPTTP53HTTALDH1A1 | |
| SCHEMBL522786 | 0.80 | CA12 (0.47) | LMNAATML3MBTL1MAPTNFKB1 | |
| SCHEMBL25072882 | 0.80 | GAA (0.46) | RAB9ALMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30278488 | 0.80 | GAA (0.46) | RAB9ALMNASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |