Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29706757 | 1.00 | MAP3K5 (0.45) | MAP3K5CRBNALOX15HTTHSD17B10 | |
| SCHEMBL29706811 | 0.92 | CRBN (0.51) | MAP3K5CRBNALOX15HTTHSD17B10 | |
| SCHEMBL23011967 | 0.82 | MAP3K5 (0.43) | MAP3K5CRBNMAPTKIF11GSK3B | |
| SCHEMBL883735 | 0.81 | RAB9A (0.42) | HTTHSD17B10MAPTTP53LMNA | |
| SCHEMBL259844 | 0.79 | SMYD3 (0.43) | CRBNGSK3BLMNAALDH1A1 | |
| SCHEMBL21155050 | 0.78 | CRBN (0.38) | CRBNALOX15HTTHSD17B10MAPT | |
| SCHEMBL22469472 | 0.77 | MAPT (0.52) | CRBNMAPTKIF11LMNAPKM | |
| SCHEMBL21155117 | 0.76 | PKM (0.45) | MAP3K5CRBNALOX15HTTHSD17B10 | |
| SCHEMBL25072882 | 0.75 | GAA (0.46) | ALOX15HTTHSD17B10MAPTTP53 | |
| SCHEMBL30278488 | 0.75 | GAA (0.46) | ALOX15HTTHSD17B10MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585616-B | Amide derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-114585616-A | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-2021031071-A1 | AMIDE DERIVATIVE AND USE THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2021-02-25 | — | — | WO | disclosed |