Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.73 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.73 |
| ▸ | ECE1 | P42892 | 2/20 | 0.58 |
| ▸ | CPA3 | P15088 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837483 | 0.89 | CTRB1 (0.73) | MMECTRB1ECE1CPA3FOLH1 | |
| SCHEMBL8837489 | 0.86 | CTRB1 (0.73) | MMECTRB1ECE1CPA3FOLH1 | |
| SCHEMBL4325212 | 0.84 | MME (1.00) | MMECTRB1ECE1 | |
| SCHEMBL4325217 | 0.84 | MME (1.00) | MMECTRB1ECE1 | |
| SCHEMBL11493557 | 0.84 | CTRB1 (1.00) | MMECTRB1ECE1CPA3 | |
| SCHEMBL3959317 | 0.83 | MAPK1 (0.68) | MMECTRB1 | |
| SCHEMBL2973301 | 0.83 | MAPK1 (0.68) | MMECTRB1 | |
| SCHEMBL3897966 | 0.83 | MAPK1 (0.68) | MMECTRB1 | |
| SCHEMBL7304189 | 0.83 | CTRB1 (0.65) | MMECTRB1ECE1CPA3FOLH1 | |
| SCHEMBL7608499 | 0.83 | CTRB1 (0.65) | MMECTRB1ECE1CPA3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674864-A | ANALGESICS; ENDOPEPTIDASE AND ENKEPHALINASE INHIBITORS; CARDIOTONIC, PSYCHOTROPIC AND HYPERTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1997-10-07 | — | — | US | disclosed |
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |