Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.76 |
| ▸ | ABL1 | P00519 | 5/20 | 0.67 |
| ▸ | BCR | P11274 | 5/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.64 |
| ▸ | EGFR | P00533 | 2/20 | 0.64 |
| ▸ | SRC | P12931 | 2/20 | 0.64 |
| ▸ | PRKACA | P17612 | 2/20 | 0.64 |
| ▸ | PRKACG | P22612 | 2/20 | 0.64 |
| ▸ | PRKACB | P22694 | 2/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8837881 | 0.98 | PRKCA (0.74) | PRKCAABL1BCRPRKCDEGFR | |
| SCHEMBL8837768 | 0.92 | PRKCA (0.76) | PRKCAABL1BCRPRKCDEGFR | |
| SCHEMBL8837816 | 0.90 | PRKCA (0.73) | PRKCAABL1BCRPRKCDEGFR | |
| SCHEMBL8837791 | 0.88 | PRKCA (0.70) | PRKCAABL1BCRPRKCDEGFR | |
| Water SCHEMBL8837728 | 0.88 | PRKCA (0.70) | PRKCAABL1BCRPRKCDEGFR | |
| SCHEMBL8837820 | 0.87 | PRKCA (1.00) | PRKCAABL1BCRPRKCDEGFR | |
| Water SCHEMBL8837792 | 0.86 | PRKCA (0.68) | PRKCAABL1BCRPRKCDEGFR | |
| SCHEMBL8837903 | 0.86 | PRKCA (0.83) | PRKCAABL1BCRPRKCDEGFR | |
| SCHEMBL8837805 | 0.85 | PRKCA (0.81) | PRKCAABL1BCRPRKCDEGFR | |
| SCHEMBL8837806 | 0.84 | ABL1 (0.74) | PRKCAABL1BCRPRKCDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | claimed |
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | disclosed |