Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 11/20 | 0.62 |
| ▸ | BCR | P11274 | 10/20 | 0.62 |
| ▸ | PRKCA | P17252 | 7/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.61 |
| ▸ | SRC | P12931 | 6/20 | 0.59 |
| ▸ | EGFR | P00533 | 3/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.53 |
| ▸ | PRKACA | P17612 | 2/20 | 0.53 |
| ▸ | PRKACG | P22612 | 2/20 | 0.53 |
| ▸ | PRKACB | P22694 | 2/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837783 | 0.92 | CSNK2A1 (0.67) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL3511553 | 0.92 | CSNK2A1 (0.66) | ABL1BCRPRKCACSNK2A1SRC | |
| Hydrochloric Acid SCHEMBL3511724 | 0.91 | CSNK2A1 (0.65) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL3514107 | 0.87 | CSNK2A1 (0.66) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL8837776 | 0.87 | ABL1 (0.70) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL8837830 | 0.87 | ABL1 (0.70) | ABL1BCRPRKCACSNK2A1SRC | |
| Hydrochloric Acid SCHEMBL3511423 | 0.86 | CSNK2A1 (0.65) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL8837787 | 0.86 | ABL1 (0.71) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL3510088 | 0.84 | CSNK2A1 (0.70) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL8837819 | 0.83 | CSNK2A1 (0.71) | ABL1BCRPRKCACSNK2A1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | claimed |
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | disclosed |