SCHEMBL883792

SCHEMBL883792

CN(C)C1CCN(N)CC1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13654343 0.84
SCHEMBL13383211 0.84
SCHEMBL13654348 0.84
SCHEMBL23119354 0.79
SCHEMBL17284223 0.79 L3MBTL3 (0.47) L3MBTL3L3MBTL1
SCHEMBL23653975 0.75 SLC6A4 (0.33)
SCHEMBL27985431 0.74 L3MBTL3 (0.42) L3MBTL3L3MBTL1TDP1
SCHEMBL46703 0.74 L3MBTL3 (0.42) L3MBTL3L3MBTL1
SCHEMBL23682812 0.72 L3MBTL3 (0.45) L3MBTL3L3MBTL1TDP1
SCHEMBL20926955 0.72 L3MBTL3 (0.41) L3MBTL3L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021216440-A1 NOVEL PROTEIN KINASE INHIBITORS TENOVA PHARMACEUTICALS INC. (US) 2021-10-28 WO disclosed
WO-2021047646-A1 SUBSTITUTED IMIDAZOQUINOXALINE COMPOUNDS AND USES THEREOF IMPACT THERAPEUTICS, INC (CN) 2021-03-18 WO disclosed
WO-2021004482-A1 SUBSTITUTED PYRAZOLOQUINAZOLONE COMPOUND AND APPLICATION THEREOF 上海瑛派药业有限公司 2021-01-14 WO disclosed
EP-3555063-B1 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2020-09-16 EP disclosed
WO-2018127195-A1 SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF 上海瑛派药业有限公司 2018-07-12 WO disclosed
WO-2018108704-A1 NEW 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2018-06-21 WO disclosed
WO-2017192228-A1 PAK1 INHIBITORS AND USES THEREOF ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) 2017-11-09 WO disclosed
EP-2882733-B1 SUBSTITUTED AZINES AS PESTICIDES NOVARTIS TIERGESUNDHEIT AG (CH) 2017-04-26 EP disclosed
US-9604984-B2 5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds, compositions and methods of use thereof GENENTECH, INC. (US) 2017-03-28 US disclosed
WO-2015177326-A1 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS WHICH ARE JAK INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2015-11-26 WO disclosed
WO-2012038081-A1 SUBSTITUTED BENZAMIDE COMPOUNDS Grünenthal GmbH (DE) 2012-03-29 WO disclosed