Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 9/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490770 | 0.86 | RET (0.57) | SERPINE1HPGDRETKMT2AEGFR | |
| SCHEMBL8490766 | 0.86 | RET (0.57) | SERPINE1HPGDRETKMT2AEGFR | |
| SCHEMBL6380172 | 0.82 | SERPINE1 (0.74) | SERPINE1HRH3KMT2AKDM4EMEN1 | |
| SCHEMBL8495025 | 0.81 | SERPINE1 (0.59) | SERPINE1HPGDHRH3KMT2A | |
| SCHEMBL6379672 | 0.80 | SERPINE1 (0.68) | SERPINE1HRH3KMT2AKDM4EMEN1 | |
| SCHEMBL6373887 | 0.79 | SERPINE1 (0.78) | SERPINE1HRH3 | |
| SCHEMBL643462 | 0.77 | KMT2A (0.63) | KMT2AEGFRERBB2KDM4EMEN1 | |
| SCHEMBL6375268 | 0.76 | SERPINE1 (0.70) | SERPINE1HPGDHRH3KMT2AKDM4E | |
| SCHEMBL6375264 | 0.76 | SERPINE1 (0.70) | SERPINE1HPGDHRH3KMT2AKDM4E | |
| Bromide SCHEMBL28850559 | 0.75 | KMT2A (0.61) | KMT2AEGFRERBB2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700804-A | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITORS | XENOVA LIMITED (GB) | 1997-12-23 | — | — | US | disclosed |