SCHEMBL8838409

SCHEMBL8838409

Cc1cnc2c(Cl)c(Cl)ccc2c1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.67
CCR5 P51681 2/20 0.67
CCR8 P51685 2/20 0.67
PSMD14 O00487 2/20 0.49
COPS5 Q92905 2/20 0.49
KDM4E B2RXH2 1/20 0.49
PARP1 P09874 1/20 0.42
CYP1A2 P05177 3/20 0.41
SLC40A1 Q9NP59 5/20 0.41
NFKBIA P25963 1/20 0.38
PDE10A Q9Y233 3/20 0.36
CYP2A6 P11509 2/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ALK Q9UM73 1/20 0.34
PDE2A O00408 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10838838 0.85 CCR1 (0.67) CCR1CCR5CCR8PSMD14COPS5
SCHEMBL6888604 0.85 CCR1 (0.67) CCR1CCR5CCR8PSMD14COPS5
SCHEMBL29890061 0.85 CCR1 (0.67) CCR1CCR5CCR8PSMD14COPS5
SCHEMBL22326612 0.81 CCR1 (0.62) CCR1CCR5CCR8PSMD14COPS5
SCHEMBL14841997 0.81 CCR1 (0.62) CCR1CCR5CCR8PSMD14COPS5
SCHEMBL30492603 0.81 CCR1 (1.00) CCR1CCR5CCR8PSMD14COPS5
SCHEMBL686948 0.81 CCR1 (1.00) CCR1CCR5CCR8PSMD14COPS5
SCHEMBL27891657 0.80 CCR1 (0.60) CCR1CCR5CCR8PSMD14COPS5
SCHEMBL30505759 0.80 CCR1 (0.39) CCR1CCR5CCR8PDE10ACYP2A6
SCHEMBL27840289 0.80 CCR1 (0.39) CCR1CCR5CCR8PDE10ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110903279-B Pyrazole compound, salt and application thereof 潍坊中农联合化工有限公司 2023-05-16 CN disclosed
US-11219214-B2 Benzosultams and analogues and their use as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2022-01-11 US disclosed
US-20200323211-A1 BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-10-15 US disclosed
US-10736321-B2 Benzosultams and analogues and their use as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-08-11 US disclosed
US-5625068-A Substituted quinoline herbicide intermediates and process AMERICAN CYANAMID COMPANY (US) 1997-04-29 US disclosed
EP-0747361-A1 Substituted quinoline herbicide intermediates and process American Cyanamid Company (US) 1996-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200323211-A1 BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES GABBR1, DPM1, CYP51A1 CCR1 4876/4885CCR5 4873/4885CCR8 4830/4885
US-10736321-B2 Benzosultams and analogues and their use as fungicides GABBR1, DPM1, CYP51A1 CCR1 4876/4885CCR5 4873/4885CCR8 4830/4885
US-11219214-B2 Benzosultams and analogues and their use as fungicides GABBR1, DPM1, CYP51A1 CCR1 4876/4885CCR5 4873/4885CCR8 4830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.