SCHEMBL8838422

SCHEMBL8838422

C=Cc1ccc(OCC(O)COC2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 2/20 0.43
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
S1PR1 P21453 2/20 0.33
NR5A1 Q13285 1/20 0.33
SPHK1 Q9NYA1 2/20 0.33
TP53 P04637 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9039433 0.83 USP2 (0.36) PLA2G4BNPC1RAB9ASMN1; SMN2SPHK1
SCHEMBL8888653 0.81 KDM4E (0.41) ALDH1A1MAPTMEN1KMT2ACHRNB2
SCHEMBL8838396 0.79 MEN1 (0.39) SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
SCHEMBL9039766 0.72 TSHR (0.32)
SCHEMBL15299847 0.71 GBA1 (0.37) ALDH1A1HPGDMAPK1TDP1GLA
SCHEMBL15299866 0.71 GBA1 (0.37) ALDH1A1HPGDMAPK1TDP1GLA
SCHEMBL2937499 0.69 CHRNB2 (0.60) PLA2G4BNPC1RAB9AMAPTNR5A1
SCHEMBL4906796 0.69 CHRNB2 (0.60) PLA2G4BNPC1RAB9AMAPTNR5A1
SCHEMBL19971155 0.69 CHRNB2 (0.60) PLA2G4BNPC1RAB9AMAPTNR5A1
SCHEMBL19971166 0.69 CHRNB2 (0.60) PLA2G4BNPC1RAB9AMAPTNR5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5665885-A FOR STABILIZING ORGANIC MATERIAL AGAINST THE DAMAGING INFLUENCE OF LIGHT, OXYGEN AND/OR HEAT CIBA-GEIGY CORPORATION (US) 1997-09-09 US disclosed
US-5637714-A OXIDATION AND HEAT RESISTANCE; PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5541274-A Polymeric adducts of hindered amine-epoxides as stabilizers CIBA-GEIGY CORPORATION (US) 1996-07-30 US disclosed
US-5457204-A For polymers CIBA-GEIGY CORPORATION (US) 1995-10-10 US disclosed
EP-0638597-A1 Polymeric adults of hindered amine-epoxydes as stabilizers CIBA-GEIGY AG (CH) 1995-02-15 EP disclosed
EP-0634399-A1 Adducts of hindered amine-epoxides as stabilisers CIBA-GEIGY AG (CH) 1995-01-18 EP disclosed