Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431603 | 0.94 | PDE10A (0.60) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7795676 | 0.78 | PDE10A (0.60) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8838373 | 0.77 | PDE10A (0.51) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| Bromide SCHEMBL8838451 | 0.76 | PDE10A (0.50) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL18229829 | 0.76 | HSP90AA1 (0.41) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30553418 | 0.76 | KDM4E (0.58) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL26964187 | 0.76 | KDM4E (0.58) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3713823 | 0.75 | PDE10A (0.60) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8488388 | 0.75 | HSP90AA1 (0.65) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29253980 | 0.75 | PDE10A (0.60) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625068-A | Substituted quinoline herbicide intermediates and process | AMERICAN CYANAMID COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0747361-A1 | Substituted quinoline herbicide intermediates and process | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | disclosed |