Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 14/20 | 0.70 |
| ▸ | LPAR1 | Q92633 | 13/20 | 0.70 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.58 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.46 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732573 | 0.84 | LPAR3 (0.97) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL370759 | 0.84 | LPAR3 (0.97) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL7813151 | 0.83 | LPAR1 (0.52) | LPAR3LPAR1LPAR2LPAR5TLR2 | |
| SCHEMBL31439420 | 0.83 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL2813163 | 0.83 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL31198159 | 0.83 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL496845 | 0.83 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL5055004 | 0.83 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL2814732 | 0.83 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 | |
| SCHEMBL10896195 | 0.83 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674646-B1 | LIPID DERIVATIVES OF PHOSPHONOACIDS FOR LIPOSOMAL INCORPORATION AND METHOD OF USE | CHIMERIX INC (US) | 2001-10-04 | — | — | EP | claimed |
| JP-H08504439-A | — | — | 1996-05-14 | — | — | JP | claimed |
| EP-0674646-A4 | LIPID DERIVATIVES OF PHOSPHONOACIDS FOR LIPOSOMAL INCORPORATION AND METHOD OF USE. | VESTAR INC (US) | 1996-01-17 | — | — | EP | claimed |
| US-5463092-A | Viricides | VESTAR, INC. (US) | 1995-10-31 | — | — | US | claimed |
| EP-0674646-A1 | LIPID DERIVATIVES OF PHOSPHONOACIDS FOR LIPOSOMAL INCORPORATION AND METHOD OF USE | NeXstar Pharmaceuticals, Inc. (US) | 1995-10-04 | — | — | EP | claimed |
| WO-1994013682-A1 | LIPID DERIVATIVES OF PHOSPHONOACIDS FOR LIPOSOMAL INCORPORATION AND METHOD OF USE | VESTAR, INC. (US) | 1994-06-23 | — | — | WO | claimed |