Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.52 |
| ▸ | CETP | P11597 | 3/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25335565 | 0.88 | LPAR1 (0.67) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL31069863 | 0.88 | LPAR1 (0.67) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL385051 | 0.88 | LPAR1 (0.67) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL10929587 | 0.86 | LPAR1 (0.64) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL4481628 | 0.85 | CETP (0.49) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL4483073 | 0.85 | CETP (0.50) | LPAR1LPAR3CETPLPAR2TLR2 | |
| SCHEMBL29014838 | 0.84 | LPAR1 (0.59) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL88391 | 0.83 | LPAR3 (0.70) | LPAR1LPAR3LPAR2LPAR5TLR2 | |
| SCHEMBL30931378 | 0.83 | LPAR1 (0.53) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL8736629 | 0.82 | LPAR1 (0.52) | LPAR1LPAR3CETPLPAR2LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674646-B1 | LIPID DERIVATIVES OF PHOSPHONOACIDS FOR LIPOSOMAL INCORPORATION AND METHOD OF USE | CHIMERIX INC (US) | 2001-10-04 | — | — | EP | disclosed |
| US-5463092-A | Viricides | VESTAR, INC. (US) | 1995-10-31 | — | — | US | disclosed |