Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18780441 | 0.93 | MAPT (0.43) | CRHBPCRHR2MCOLN3HSP90AA1MMP2 | |
| SCHEMBL17329231 | 0.86 | MEN1 (0.52) | — | |
| SCHEMBL17329230 | 0.86 | MEN1 (0.52) | — | |
| SCHEMBL4669533 | 0.85 | ALDH1A1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17329197 | 0.85 | PIK3CD (0.46) | MMP2MMP9 | |
| SCHEMBL7417712 | 0.85 | ALDH1A1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9153465 | 0.85 | ALDH1A1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17329225 | 0.85 | PIK3CD (0.46) | MMP2MMP9 | |
| SCHEMBL17205636 | 0.84 | USP2 (0.48) | MMP2MMP9PSEN1PSEN2APH1B | |
| SCHEMBL18709336 | 0.83 | CA12 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650428-A | THROMBOXANE A2 ANTAGONISM | NKK CORPORATION (JP) | 1997-07-22 | — | — | US | disclosed |