SCHEMBL8840384

SCHEMBL8840384

Cc1ccc(S(=O)(=O)OC2CCC3(CCCCC3)CC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.49
KMT2A Q03164 1/20 0.49
CYP1A2 P05177 1/20 0.45
ALDH1A1 P00352 6/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 1/20 0.41
POLB P06746 3/20 0.40
TP53 P04637 1/20 0.40
ENPP3 O14638 2/20 0.39
ENPP1 P22413 2/20 0.39
ENPP2 Q13822 2/20 0.39
HPGD P15428 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
CYP2C19 P33261 1/20 0.38
ACHE P22303 1/20 0.38
KDM4E B2RXH2 1/20 0.37
STS P08842 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22125738 0.92 CYP2D6 (0.57) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1
SCHEMBL26090954 0.85 KMT2A (0.51) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1
SCHEMBL11107669 0.84 CYP2D6 (0.61) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1
SCHEMBL22621292 0.84 CYP2D6 (0.61) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1
SCHEMBL9060935 0.84 CYP2D6 (0.61) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1
SCHEMBL23192021 0.84 CYP2D6 (0.61) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1
SCHEMBL8367865 0.84 CYP2D6 (0.61) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1
SCHEMBL24250706 0.84 CYP2D6 (0.61) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1
SCHEMBL8370244 0.84 CYP2D6 (0.61) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1
SCHEMBL361129 0.84 CYP2D6 (0.61) CYP2D6SMN1; SMN2KMT2ACYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650417-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-07-22 US disclosed
EP-0719255-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
EP-0719256-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995007891-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed
WO-1995007890-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed