Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840461 | 1.00 | FGFR2 (0.41) | FGFR2ALDH1A1MEN1LMNAGAA | |
| SCHEMBL8840574 | 0.90 | FGFR2 (0.33) | FGFR2ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL8840569 | 0.90 | FGFR2 (0.33) | FGFR2ALDH1A1MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL8415218 | 0.88 | FGFR2 (0.43) | FGFR2ALDH1A1MEN1LMNAGAA | |
| Hydrochloric Acid SCHEMBL8415219 | 0.88 | FGFR2 (0.43) | FGFR2ALDH1A1MEN1LMNAGAA | |
| Hydrochloric Acid SCHEMBL8840530 | 0.88 | FGFR2 (0.32) | FGFR2NSD2 | |
| Hydrochloric Acid SCHEMBL8840518 | 0.88 | FGFR2 (0.32) | FGFR2NSD2 | |
| SCHEMBL8840592 | 0.86 | GRM1 (0.33) | FGFR2GRM1NSD2DRD2DRD3 | |
| SCHEMBL8840570 | 0.86 | FGFR2 (0.37) | FGFR2ALDH1A1MEN1LMNAGAA | |
| SCHEMBL8840573 | 0.86 | FGFR2 (0.37) | FGFR2ALDH1A1MEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |