Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840574 | 1.00 | FGFR2 (0.33) | FGFR2NSD2GAAGRM1KDM4E | |
| SCHEMBL8840466 | 0.90 | FGFR2 (0.41) | FGFR2NSD2GAAGRM1MEN1 | |
| SCHEMBL8840461 | 0.90 | FGFR2 (0.41) | FGFR2NSD2GAAGRM1MEN1 | |
| Hydrochloric Acid SCHEMBL8840518 | 0.89 | FGFR2 (0.32) | FGFR2NSD2 | |
| Hydrochloric Acid SCHEMBL8840530 | 0.89 | FGFR2 (0.32) | FGFR2NSD2 | |
| SCHEMBL8705285 | 0.85 | NSD2 (0.35) | FGFR2NSD2GAAGRM1KDM4E | |
| SCHEMBL8705288 | 0.85 | NSD2 (0.35) | FGFR2NSD2GAAGRM1KDM4E | |
| SCHEMBL8840391 | 0.83 | NSD2 (0.33) | NSD2GAA | |
| SCHEMBL8840388 | 0.83 | NSD2 (0.33) | NSD2GAA | |
| SCHEMBL8840592 | 0.83 | GRM1 (0.33) | FGFR2NSD2GRM1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |