Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.32 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840561 | 1.00 | NSD2 (0.35) | NSD2KMT5BKMT5CKDM4EMEN1 | |
| SCHEMBL8840599 | 1.00 | NSD2 (0.35) | NSD2KMT5BKMT5CKDM4EMEN1 | |
| SCHEMBL8840560 | 0.89 | FGFR2 (0.39) | NSD2KMT5BKMT5CKDM4EMEN1 | |
| SCHEMBL8706891 | 0.87 | NSD2 (0.39) | NSD2KMT5BKMT5CKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL8840530 | 0.86 | FGFR2 (0.32) | NSD2FGFR2 | |
| Hydrochloric Acid SCHEMBL8840518 | 0.86 | FGFR2 (0.32) | NSD2FGFR2 | |
| SCHEMBL8705389 | 0.82 | NSD2 (0.38) | NSD2KMT5BKMT5CKDM4EMEN1 | |
| SCHEMBL9034335 | 0.80 | NSD2 (0.36) | NSD2KMT5BKMT5CKDM4EMEN1 | |
| SCHEMBL8710322 | 0.80 | NSD2 (0.36) | NSD2KMT5BKMT5CKDM4EMEN1 | |
| SCHEMBL8705183 | 0.80 | NSD2 (0.36) | NSD2KMT5BKMT5CKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |