Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.35 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414952 | 0.85 | NSD2 (0.39) | NSD2KMT5BKMT5CKDM4EALDH1A1 | |
| SCHEMBL8414953 | 0.85 | NSD2 (0.39) | NSD2KMT5BKMT5CKDM4EALDH1A1 | |
| SCHEMBL8706891 | 0.85 | NSD2 (0.39) | NSD2KMT5BKMT5CKDM4EALDH1A1 | |
| SCHEMBL8705183 | 0.84 | NSD2 (0.36) | NSD2KMT5BKMT5CKDM4EALDH1A1 | |
| SCHEMBL9035638 | 0.83 | FGFR2 (0.34) | NSD2CYP2D6CYP2C19NOS1NOS2 | |
| SCHEMBL9035632 | 0.83 | FGFR2 (0.34) | NSD2CYP2D6CYP2C19NOS1NOS2 | |
| SCHEMBL8840599 | 0.82 | NSD2 (0.35) | NSD2KMT5BKMT5CKDM4EALDH1A1 | |
| SCHEMBL8840567 | 0.82 | NSD2 (0.35) | NSD2KMT5BKMT5CKDM4EALDH1A1 | |
| SCHEMBL8840561 | 0.82 | NSD2 (0.35) | NSD2KMT5BKMT5CKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8710432 | 0.82 | FGFR2 (0.34) | NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723450-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0719256-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007891-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |