⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840521 | 0.91 | KMT2A (0.33) | — | |
| SCHEMBL8840431 | 0.88 | — | — | |
| SCHEMBL8840484 | 0.84 | KDM4E (0.33) | — | |
| SCHEMBL8840493 | 0.81 | AVPR1A (0.31) | — | |
| SCHEMBL9033980 | 0.81 | — | — | |
| SCHEMBL8840430 | 0.80 | KMT2A (0.33) | — | |
| SCHEMBL9035111 | 0.79 | PRMT5 (0.31) | — | |
| SCHEMBL27449186 | 0.79 | KMT2A (0.33) | — | |
| SCHEMBL8840494 | 0.73 | KMT2A (0.34) | — | |
| SCHEMBL8840417 | 0.73 | GRM2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |