Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 2/20 | 0.31 |
| ▸ | GIPR | P48546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840493 | 0.92 | AVPR1A (0.31) | AVPR1APRMT5 | |
| SCHEMBL8840380 | 0.87 | KDM4E (0.34) | AVPR1APRMT5 | |
| SCHEMBL8840430 | 0.85 | KMT2A (0.33) | KMT2ANPBWR1MCHR1MEN1ALDH1A1 | |
| SCHEMBL8840550 | 0.84 | L3MBTL1 (0.35) | KMT2ANPBWR1MCHR1 | |
| SCHEMBL8840416 | 0.84 | TP53 (0.35) | AVPR1APRMT5 | |
| SCHEMBL9035111 | 0.80 | PRMT5 (0.31) | PRMT5 | |
| SCHEMBL8840521 | 0.79 | KMT2A (0.33) | KMT2ANPBWR1MCHR1MEN1ALDH1A1 | |
| SCHEMBL27449186 | 0.76 | KMT2A (0.33) | KMT2ANPBWR1MCHR1MEN1ALDH1A1 | |
| SCHEMBL9033980 | 0.74 | — | — | |
| SCHEMBL8840575 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |