Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4088388 | 1.00 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2ANOS1 | |
| SCHEMBL13006769 | 1.00 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2ANOS1 | |
| SCHEMBL69669 | 1.00 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2ANOS1 | |
| SCHEMBL23352964 | 1.00 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2ANOS1 | |
| SCHEMBL18900975 | 1.00 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2ANOS1 | |
| SCHEMBL23221351 | 1.00 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2ANOS1 | |
| SCHEMBL13007137 | 1.00 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2ANOS1 | |
| SCHEMBL23561000 | 1.00 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2ANOS1 | |
| Hydrochloric Acid SCHEMBL3423904 | 0.97 | ALDH1A1 (0.50) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL22348939 | 0.97 | ALDH1A1 (0.50) | ALDH1A1THRBMEN1KMT2ANOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3560499-A1 | DIHYDROPTERIDINONES FOR THE TREATMENT OF CANCER DISEASES | Boehringer Ingelheim International GmbH (DE) | 2019-10-30 | — | — | EP | disclosed |
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |