Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15459214 | 0.97 | KDM4E (0.52) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL22432963 | 0.87 | HTT (0.52) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL26437113 | 0.85 | CYP1A2 (0.55) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL70123 | 0.82 | MAPT (0.75) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL47929 | 0.79 | ALDH1A1 (0.61) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL25971408 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL29600339 | 0.76 | KDM4E (0.67) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL1259029 | 0.76 | KDM4E (0.67) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL395019 | 0.76 | KDM4E (0.67) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 | |
| SCHEMBL13672151 | 0.75 | KDM4E (0.50) | KDM4EALDH1A1CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637669-A | THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-06-10 | — | — | US | disclosed |