Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 5/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834673 | 0.81 | PRMT5 (0.33) | PRMT5TP53FFAR1ESR1PDE5A | |
| SCHEMBL7838282 | 0.79 | PPARG (0.48) | TP53FFAR1PPARGPPARARARG | |
| SCHEMBL7831922 | 0.68 | MEN1 (0.33) | TP53FFAR1PPARGPPARAMEN1 | |
| SCHEMBL1130956 | 0.67 | FFAR1 (0.54) | TP53FFAR1PPARGPPARAMEN1 | |
| SCHEMBL7833699 | 0.65 | PPARG (0.33) | FFAR1ESR1PPARGPPARARARG | |
| SCHEMBL6544217 | 0.63 | PPARG (0.47) | FFAR1PPARGPPARARARGRXRA | |
| SCHEMBL7241918 | 0.63 | FFAR1 (0.54) | FFAR1PPARGPPARA | |
| SCHEMBL7833485 | 0.63 | PPARG (0.46) | TP53FFAR1PPARGPPARARXRA | |
| Hydrochloric Acid SCHEMBL7244641 | 0.63 | FFAR1 (0.53) | FFAR1PPARGPPARA | |
| Hydrochloric Acid SCHEMBL6544449 | 0.62 | PPARG (0.46) | FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |