Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25915803 | 0.79 | ELANE (0.48) | — | |
| SCHEMBL12096479 | 0.78 | PARP1 (0.31) | DYRK1A | |
| SCHEMBL14639241 | 0.78 | ELANE (0.42) | — | |
| SCHEMBL27306258 | 0.73 | ELANE (0.46) | — | |
| SCHEMBL31441038 | 0.71 | PARP1 (0.33) | DYRK1A | |
| SCHEMBL10699206 | 0.71 | PARP1 (0.33) | DYRK1A | |
| SCHEMBL30629629 | 0.71 | PARP1 (0.33) | DYRK1A | |
| SCHEMBL2115053 | 0.71 | NCF1 (0.41) | DYRK1A | |
| SCHEMBL17983448 | 0.69 | ELANE (0.38) | — | |
| SCHEMBL4586031 | 0.69 | CNR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622945-A | Rubyrin macrocycles | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1997-04-22 | — | — | US | disclosed |
| WO-1996021665-A1 | TURCASARINS, NOVEL EXPANDED PORPHYRINS, AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-07-18 | — | — | WO | disclosed |
| US-5410045-A | As anion chelators, receptors and transporters | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-04-25 | — | — | US | disclosed |