Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | GHSR | Q92847 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294068 | 0.86 | TP53 (0.59) | TP53LMNAOPRK1KCNH2HTR1A | |
| SCHEMBL11769344 | 0.85 | TP53 (0.72) | TP53LMNAOPRK1KCNH2HTR1A | |
| SCHEMBL11577976 | 0.84 | TP53 (0.65) | TP53LMNAOPRK1KCNH2HTR1A | |
| SCHEMBL11579072 | 0.83 | TP53 (0.64) | TP53LMNAOPRK1KCNH2HTR1A | |
| SCHEMBL11577333 | 0.83 | TP53 (0.64) | TP53LMNAOPRK1KCNH2HTR1A | |
| SCHEMBL27405126 | 0.82 | TP53 (0.69) | TP53LMNAOPRK1KCNH2HTR1A | |
| SCHEMBL11770839 | 0.82 | TP53 (0.69) | TP53LMNAOPRK1KCNH2HTR1A | |
| SCHEMBL7408994 | 0.82 | TP53 (0.63) | TP53LMNAOPRK1KCNH2HTR1A | |
| SCHEMBL11581617 | 0.82 | TP53 (0.63) | TP53LMNAOPRK1KCNH2HTR1A | |
| SCHEMBL11748770 | 0.81 | TP53 (0.62) | TP53LMNAOPRK1KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662911-A | USED AS IMMUNOGENS TO OBTAIN ANTIBODIES TO BENZODIAZEPINES | BOEHRINGER MANNHEIM GMBH (DE) | 1997-09-02 | — | — | US | disclosed |