Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16836639 | 0.89 | PTPN11 (0.60) | PTPN11S1PR3PTPN1PTPN6PLA2G2A | |
| SCHEMBL9011630 | 0.85 | CYP3A4 (0.54) | PTPN11S1PR3PLA2G2AMEN1NR1I2 | |
| SCHEMBL8167721 | 0.84 | PTPN11 (0.61) | PTPN11S1PR3PTPN1PTPN6PLA2G2A | |
| SCHEMBL9004517 | 0.83 | THRB (0.48) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL2201723 | 0.83 | TLR8 (0.43) | PLA2G2AALDH1A1HPGDMEN1NR1I2 | |
| Hydrochloric Acid SCHEMBL8154036 | 0.82 | PTPN11 (0.60) | PTPN11S1PR3PTPN1PTPN6PLA2G2A | |
| Hydrochloric Acid SCHEMBL9038246 | 0.82 | PTPN11 (0.60) | PTPN11S1PR3PTPN1PTPN6PLA2G2A | |
| SCHEMBL668981 | 0.82 | PTPN11 (0.64) | PTPN11S1PR3PTPN1PTPN6PLA2G2A | |
| SCHEMBL10539639 | 0.82 | PTPN11 (0.64) | PTPN11S1PR3PTPN1PTPN6PLA2G2A | |
| SCHEMBL4462194 | 0.82 | PTPN11 (0.64) | PTPN11S1PR3PTPN1PTPN6PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637669-A | THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0670856-A1 | THERMOSETTABLE COMPOSITION CONTAINING MESOGENIC MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994012556-A2 | THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1994-06-09 | — | — | WO | disclosed |