SCHEMBL8840940

SCHEMBL8840940

c1ccc2c(OCC3CO3)c(OCC3CO3)c(OCC3CO3)cc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
GLA P06280 1/20 0.51
TDP1 Q9NUW8 1/20 0.47
TP53 P04637 3/20 0.46
TSHR P16473 3/20 0.46
HIF1A Q16665 2/20 0.46
CYP3A4 P08684 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
PDK1 Q15118 1/20 0.38
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
PTPN1 P18031 1/20 0.36
CYP1A2 P05177 1/20 0.36
PPARG P37231 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
FGFR1 P11362 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31120494 1.00 ALDH1A1 (0.51) ALDH1A1GLATDP1TP53TSHR
SCHEMBL19612189 0.90 ALDH1A1 (0.48) ALDH1A1GLATDP1TP53TSHR
SCHEMBL3952927 0.88 ALDH1A1 (0.49) ALDH1A1GLATDP1TP53TSHR
SCHEMBL19612268 0.88 TDP1 (0.53) ALDH1A1GLATDP1TP53TSHR
SCHEMBL464600 0.87 TDP1 (0.53) ALDH1A1GLATDP1TP53TSHR
SCHEMBL9230703 0.87 ALDH1A1 (0.48) ALDH1A1GLATDP1TP53TSHR
SCHEMBL19612244 0.86 ALDH1A1 (0.53) ALDH1A1GLATDP1TP53TSHR
SCHEMBL8847178 0.84 ALDH1A1 (0.54) ALDH1A1GLATDP1TP53TSHR
SCHEMBL15954516 0.84 TDP1 (0.46) ALDH1A1GLATDP1TP53TSHR
SCHEMBL19612250 0.84 TDP1 (0.46) ALDH1A1GLATDP1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5637669-A THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-06-10 US disclosed
EP-0670856-A1 THERMOSETTABLE COMPOSITION CONTAINING MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP disclosed
WO-1994012556-A2 THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1994-06-09 WO disclosed