Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10955603 | 0.91 | TSHR (0.41) | TSHRCYP3A4NPSR1GLO1SMN1; SMN2 | |
| SCHEMBL10955612 | 0.86 | TSHR (0.38) | TSHRCYP3A4NPSR1GLO1SMN1; SMN2 | |
| SCHEMBL9807869 | 0.86 | GLO1 (0.47) | TSHRCYP3A4NPSR1GLO1SMN1; SMN2 | |
| SCHEMBL9807872 | 0.86 | GLO1 (0.47) | TSHRCYP3A4NPSR1GLO1SMN1; SMN2 | |
| SCHEMBL8832099 | 0.83 | NPSR1 (0.50) | TSHRCYP3A4NPSR1GLO1SMN1; SMN2 | |
| SCHEMBL28537688 | 0.77 | TSHR (0.39) | TSHRCYP3A4SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL10966895 | 0.74 | CYP3A4 (0.45) | TSHRCYP3A4NPSR1SMN1; SMN2PKM | |
| SCHEMBL21980975 | 0.74 | CYP3A4 (0.45) | TSHRCYP3A4NPSR1SMN1; SMN2PKM | |
| SCHEMBL1566521 | 0.73 | CYP2C9 (0.45) | TSHRNPSR1SMN1; SMN2PKMALDH1A1 | |
| SCHEMBL1566520 | 0.73 | CYP2C9 (0.45) | TSHRNPSR1SMN1; SMN2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599772-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5565412-A | (2-imidazolin-2-yl) fused heteropyridine compounds, intermediates for the preparation of and use of said compounds as herbicidal agents | AMERICAN CYANAMID CO. (US) | 1996-10-15 | — | — | US | disclosed |