SCHEMBL8841547

SCHEMBL8841547

CCCCC(C)Cc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 12/20 0.62
ALDH1A1 P00352 2/20 0.59
MEN1 O00255 1/20 0.59
RARA P10276 1/20 0.59
MAPT P10636 1/20 0.59
MTOR P42345 1/20 0.59
KMT2A Q03164 1/20 0.59
ADRB1 P08588 1/20 0.48
ADRB3 P13945 1/20 0.48
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
LTB4R2 Q9NPC1 1/20 0.47
NPC1 O15118 1/20 0.47
NFKB1 P19838 1/20 0.47
RAB9A P51151 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
BDKRB2 P30411 1/20 0.46
MME P08473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11654567 0.91 RARB (0.57) RARBALDH1A1MEN1RARAMAPT
SCHEMBL28261661 0.89 RARB (0.56) RARBALDH1A1MEN1RARAMAPT
SCHEMBL9717269 0.86 RARB (0.69) RARBALDH1A1MEN1RARAMAPT
SCHEMBL9335694 0.84 RARB (0.56) RARBALDH1A1MEN1RARAMAPT
SCHEMBL3084046 0.84 RARB (0.56) RARBALDH1A1MEN1RARAMAPT
SCHEMBL11658538 0.84 RARB (0.60) RARBALDH1A1MEN1RARAMAPT
SCHEMBL10485692 0.83 GRIN2D (0.54) RARBALDH1A1ADRB1ADRB3NFKB1
SCHEMBL10485816 0.81 GRIN2D (0.52) RARBALDH1A1ADRB1ADRB3
SCHEMBL10601735 0.81 GRIN2D (0.52) RARBALDH1A1ADRB1ADRB3
SCHEMBL10415558 0.80 RARB (0.67) RARBALDH1A1MEN1RARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5602660-A Ferroelectric liquid crystal apparatus having negative dielectric anisotropy and colored film at non-pixel portions CANON KABUSHIKI KAISHA (JP) 1997-02-11 US disclosed
US-5461494-A Ferroelectric liquid crystal device having colored film and protective film at non-pixel portions CANON KABUSHIKI KAISHA (JP) 1995-10-24 US disclosed