Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 18/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842711 | 0.82 | ACHE (0.69) | ACHE | |
| SCHEMBL8842342 | 0.81 | ACHE (0.73) | ACHE | |
| SCHEMBL8841980 | 0.80 | ACHE (0.68) | ACHE | |
| SCHEMBL8842702 | 0.78 | ACHE (0.68) | ACHE | |
| SCHEMBL8842323 | 0.71 | ACHE (0.57) | ACHE | |
| SCHEMBL2405165 | 0.69 | ACHE (0.58) | ACHE | |
| SCHEMBL29868981 | 0.69 | ACHE (0.58) | ACHE | |
| SCHEMBL2405318 | 0.69 | ACHE (0.58) | ACHE | |
| SCHEMBL29868439 | 0.69 | ACHE (0.58) | ACHE | |
| SCHEMBL8873135 | 0.69 | ACHE (0.58) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594002-A | Benzazabicyclic carbamates as novel cholinesterase inhibitors | PFIZER INC (US) | 1997-01-14 | — | — | US | disclosed |
| US-5387590-A | Benzazabicyclic carbamates as novel cholinesterase inhibitors | PFIZER INC. (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1991003467-A1 | BENZAZABICYCLIC CARBAMATES AS NOVEL CHOLINESTERASE INHIBITORS | PFIZER INC. (US) | 1991-03-21 | — | — | WO | disclosed |
| EP-0415634-A2 | Benzazabicyclic carbamates as cholinesterase inhibitors | PFIZER INC. (US) | 1991-03-06 | — | — | EP | disclosed |